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BIOL_SCI 301 Biochemistry (1): Major areas and principles of biochemical processes at the molecular level: structure, metabolism, energetics, and control mechanisms.
BIOL_SCI 302 Fundamentals of Neurobiology (1): Cellular and biophysical approaches to the nervous system; neuron structure and function; mechanisms underlying cell-cell communication.
BIOL_SCI 303 Molecular Neurobiology (1): How the methods of cell and molecular biology are applied to neural cells, focusing on the molecular basis for nerve cell signaling, how neurons make and modify their axons, dendrites, and synapses, and the molecular aberrations that underlie nerve cell death in Alzheimer's disease.
BIOL_SCI 304 Developmental Neurobiology (1): Cellular aspects of nervous system development; relationship between structure and function during development.
BIOL_SCI 305 Neurobiology Laboratory (1): Hands-on experience in the performance of classical experiments in cellular neurophysiology. Laboratory course. Prerequisites: BIOL_SCI 302 or permission of instructor.
BIOL_SCI 306 Central Nervous System Physiology (1): Integrative approach to understanding functions of the mammalian central nervous system. Neural control of homeostatic processes. Hypothalamic and autonomic regulatory systems in stress, temperature regulation, feeding, and reproduction.
BIOL_SCI 308 Neuroanatomy (1): Examine the organization and morphology of the nervous system. Levels considered will extend from single neurons through simple nervous systems in invertebrates to lower vertebrates and the mammalian nervous system. Emphasis will be placed on the mammalian nervous system.
BIOL_SCI 311 ISP Neurobiology (1): General introduction to the physiology of the mammalian brain. Begins with a detailed look at membrane properties of single neurons and at synaptic transmission. Continues with mechanisms of basic sensory and motor processes in the brain. Not approved for IBiS students.
BIOL_SCI 315 Cell Biology (1): Relationship of shape, structural dynamics, and function with the cellular state and gene expression; cell cycle, chromosome structure, nuclear matrix, cytoskeleton, organelles, nucleocytoplasmic interaction, cell-cell communication, and movement of molecules across membranes.
BIOL_SCI 321 Physical Biochemistry (1): Physical chemistry for biological sciences majors. Topics include fundamental principles of thermodynamics, molecular motion and transport properties and kinetics, using examples of biological macromolecules.
BIOL_SCI 322 Biochemistry of Macromolecular Complexes (1): Structure determinations and features observed in proteins; functional properties examined in terms of structure; DNA binding proteins used to exemplify these relationships in biological systems.
BIOL_SCI 323 Bioinformatics: Sequence and Structure Analysis (1): An introductory course exploring the principles and applications of computational tools to research problems in biology. Prerequisites: Introductory-level biochemistry, protein structure and function, and some background in discrete mathematics, statistics, and probability; BIOL_SCI 301 or equivalent; BIOL_SCI 361 or equivalent; and permission of instructor.
BIOL_SCI 324 Neurobiology of Biological Clocks (1): Properties and roles of biological clocks in living systems; general properties of clocks; how clocks are used to time diverse activities of the cell, the organ, and the organism; neural basis for the generation of circadian rhythms; importance of biological rhythms to human health.
BIOL_SCI 325 Systems Physiology (1): Physiological principles and mechanisms responsible for the ability of animals to regulate variables in the steady state and to survive alterations in the external environment.
BIOL_SCI 326 Neurobiology of Learning and Memory (1): Basic physiological principles of brain function, technologies used to image brain function, and their application. Prerequisites: Permission of instructor; highly recommended: neuroanatomy, biochemistry, and calculus.
BIOL_SCI 333 Microbial Cell and Molecular Biology (1): Structure, growth, metabolism, and genetics of prokaryotic organisms. Contemporary computer-based strategies for investigating their molecular biology.
BIOL_SCI 334 Vertebrate Histology (1): Tissues and microscopic anatomy of organs and organ systems; origins of tissues and organs; relation of structure to function.
BIOL_SCI 340 Biological Basis of Disease (1): Cellular responses to injury; biology of cancer; inflammation and immunity; developmental pathology.
BIOL_SCI 346 Field Ecology (1): This is an outdoor lab course, providing a field experience for students in biological and environmental sciences. Prerequisites: BIOL 204 is preferred, but BIOL 210-1 or 164-0 also accepted; STAT 202, 206, or 210 are preferred, but MATH 214-3 also accepted.
BIOL_SCI 354 Advanced Biochemistry and Biophysics Laboratory (1): Project-based approach to the functional characterization of proteins, using multiple spectroscopic tools and other quantitative biochemical methods. Includes an overview of structure determination by x-ray diffraction and by NMR. Prerequisites: BIOL_SCI 210-1,2,3 and BIOL_SCI 301.
BIOL_SCI 355 Immunobiology (1): Nature and mechanisms of natural and acquired host resistance, including hormonal and cellular immunity; characteristics of antigens, antibodies, and their interaction; ontogeny and the cellular basis of the immune response; hypersensitivity; specific immunologic paralysis and transplantation.
BIOL_SCI 356 Vertebrate Endocrinology (1): Physiology and biochemistry of glands of internal secretion in vertebrates. Hormone structure, measurement, function, and interrelationships among endocrine glands.
BIOL_SCI 360 Biophysics of Living Systems (1): Function of biological systems from the physical point of view. Emphasis on macroscopic functions such as locomotion, hearing, and breathing, and on physical methods to measure such functions.
BIOL_SCI 361 Proteins and Nucleic Acids (1): Structure and function of biological macromolecules; methods of structural determination for biological macromolecules. Prerequisites: BIOL_SCI 301 and permission of instructor.
BIOL_SCI 362 Biophysics of Macromolecular Systems (1): Content varies. Examples include physical chemistry in cells, molecular architecture, subcellular architecture, molecular machines, and biophysical methods. May be repeated for credit with change of topic.
BIOL_SCI 377 Sensory Neurobiology (1): Physiological process in sensory receptor cells; chemical senses, vision, hearing, and lateral line organs; analysis of specialized sensory systems.
BIOL_SCI 378 Functional Genomics (1): Examines the study of whole genomes including structural genomics (genetic, physical and sequence maps), functional genomics (gene discovery, expression profiling, proteomics), and bioinformatics. Prerequisites: Permission of instructor.
BIOL_SCI 390 Molecular Biology I (1): Nucleic acid and chromosome structure; cell and virus genetics; mechanisms and control of DNA mutation, repair, recombination, replication, restriction and modification, and lysogeny; recombinant DNA technology and gene cloning.
BIOL_SCI 391 Developmental Biology (1): Molecular mechanisms underlying early embryonic development, including establishment of the body and organogenesis. Discussion of primary literature.
BIOL_SCI 392 Developmental Biology (1): Application of genetics and molecular biology to examine early embryonic development; gametogenesis, morphogenetic determinants in egg cytoplasm, early embryonic gene activity, and transcriptional and translational regulation. Lecture and laboratory.
BIOL_SCI 393 Molecular Biology of Disease Seminar (1): Selected topics in cytogenetics, including polytene chromosomes. Activation of gene transcription, Balbiani rings, the Drosophila heat shock system, lampbrush chromosomes, insect oogenesis and its genetic control, spermatogenesis, and dosage compensation.
BIOL_SCI 395 Molecular Genetics (1): Modern genetic analysis in studies of cell biology, development, and human disease. Emphasis on interpretation of experimental results.
IBIS 401 Molecular Biophysics (1): Protein structure; nucleic acids structure; transport and diffusion; macromolecular assemblies; molecular machines and single molecule studies; x-ray crystallography; electron microscopy and image reconstruction; nuclear magnetic resonance.
IBIS 402 Molecular Biology and Development (1): Gene structure and regulation; transcription and its control, RNA processing, and translational regulation; DNA replication and its control; genome rearrangements; developmental control of gene expression; molecular analysis of disease.
IBIS 403 Eukaryotic Genetics (1): This course focuses on the use of genetic variation among organisms to identify the genes that are essential for the functioning of biological systems such as regulation of blood pressure, circadian rhythms and memory and to identify the genes that are responsible for human diseases and biological variation among people. Mapping and cloning of genes, haplotype analysis, the use of genetic manipulation and expression analysis are among the specific topics that are covered in order to achieve the course's main goals. Homework is due prior to each class meeting and students are expected to make individual presentations covering specific topics from original research articles. Lectures on one day are given to prepare students for reading original articles that will be discussed the next day.
IBIS 404 Principles and Methods in Animal Development (1): Major concepts of embryogenesis in model animals; axis formation; cell-to-cell signaling; tissue patterning; stem cells. Emphasis on experimental principles.
IBIS 405 Chemistry, Physics, and the Biology of Molecular Machines (1): Protein synthesis will be used to illustrate how chemistry, structural biology, molecular genetics and enzymology are combined to describe a complex molecular machine.
IBIS 406 Cell Biology (1): Solid background knowledge in key areas of modern cell biology will be taught and then used to critically evaluate primary literature.
IBIS 407 Genome Scale Science: Analysis of Transcription, Proteomes, and Phenotypes (1): Contemporary large scale approaches to biological research problems, including whole-genome transcriptional profiling, proteomic analysis, and high-throughput phenotypic screening.
IBIS 408 Fundamentals of Macromolecular Crystallography and NMR (1): Exploring the principles and practical application of macromolecular crystallography and NMR in structural biology research. Students will learn practical aspects of the design and performance of experiments and processing and analysis of data.
IBIS 409 Biophysical Methods for Studying Macromolecules and Their Interactions (1): Principles and practical applications of biophysical methods in biological research, emphasizing macromolecular structure and function;techniques include fluorescence spectroscopy, CD, analytical centrifugation, surface plasmaon resonance, EM, MS..etc.Intstrumentation in NU Keck Biophysics Facility.
IBIS 411 Research Seminar in Sensory Physiology (1): Recent research in sensory processes.
IBIS 416 Nerve Cell Growth and Synapse Formation (1): Seminar concerning the molecular cell biology of axon outgrowth and synaptogenesis.
IBIS 417 Alzheimer's Disease and the Mechanisms of Cell Death (1): Seminar concerning the molecular biology of Alzheimer's disease. Emphasizes teamwork in the analysis of state-of-the-art research articles and creation of novel theories and research strategies.
IBIS 419 Biology of Animal Viruses (1): Virus structure, synthesis of viral nucleic acids and proteins, the interaction of viral and cellular genomes, and structural and functional alteration of virus-infected cells.
IBIS 455 Special Topics (0-1) : Topics change quarterly. May be repeated for credit with change of topic.
IBIS 462 Seminar in Biological Sciences (0): Lectures by nationally known investigators on recent developments within their fields and on current research projects in their laboratories. Question-and-answer session, followed by a reception for students and speakers.
IBIS 480 Mammalian Reproduction (1): Molecular, cellular, physiological, and behavioral aspects of mammalian reproduction; comparison of strategies used by mammals in reproductive processes ranging from gamete production to neural control of reproductive hormones and behavior. Prerequisites: Permission of instructor and department.
IBIS 499 Independent Study: Laboratory Rotation (1-3) : Permission of instructor and department required.
IBIS 590 Research (1-3) : Independent investigation of selected problems pertaining to thesis or dissertation.
Related Courses
NUIN 401-1,2,3 Fundamentals of Neuroscience (1): A broad, team-taught review of neuroscience. Topics include cellular and molecular neuroscience, nervous system development, sensory systems, motor systems, regulatory systems, behavioral and cognitive neuroscience. Required for first year NUIN students. (NUIN 401-2 may be taken for 2.5 credit with approved lab section).
NUIN 433 The Neurobiology of Disease (1): The goal of the course is to learn about diseases and disorders of the nervous system, and will involve patient presentations and basic and clinical lectures.
NUIN 434 Molecular and Cellular Basis of Developmental Neurobiology (1): An advanced graduate level course that will emphasize molecular neurobiological approaches to neural development.
NUIN 440 Advanced Neuroanatomy (1): Structure of the mammalian central nervous system, excluding gross morphology, functional systems, and chemical pathways. Modern experimental question s and approaches emphasized. Laboratories include a dissection of the human brain.
NUIN 447 Neural Plasticity (1): Discussion-based course covering classic and current concepts in neural plasticity. Structural, electrophysiological and functional plasticity of neural circuitry will be studied in relation to issues such as sensory adaptation, learning and neural responses to injury. Evaluation based on class participation, oral presentation, and a paper.
NUIN 452 Sensorimotor Integration (1): Skeletomotor and oculomotor control processes and their relation to sensory signals. Topics range from classic accounts of motor performance to microelectrode studies in behaving animals.
NUIN 455 Instrumentation for Neuroscience (1): Equipment used in neuroscience research, with emphasis on custom-built electronic, mechanical, and computer devices. Basic theory applicable to cellular neuroscience. Practical points applicable to systems or behavioral neuroscience. Hands-on practice.
NUIN 470 Cellular and Molecular Basis of Information Storage (1): Students will read and discuss primary literature focusing on the cellular and molecular basis of memory, specifically memory for space, associations and fear. Synaptic plasticity, the role of genes in memory and modern experimental techniques for understanding memory will also be discussed.
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