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Postdoctoral Fellowship Available at the Children's Hospital of Philadelphia

Modified: March 30, 2015

A Postdoctoral Fellow position is available in the laboratory of Dr. John M. Maris, exploring the genetic basis of childhood neuroblastoma at the Children's Hospital of Philadelphia.

Dr. Maris is the D’Angio Endowed Professor and Principal Investigator in the Division of Oncology. The successful postdoctoral applicant will join a multi-disciplinary team seeking to understand the genetic basis of the childhood cancer neuroblastoma. Specifically, the successful candidate will be the lead scientist on a new R01 focused on the LMO1 oncogene, discovered by the Maris lab as a major driver of neuroblastoma tumorigenesis (Wang et al., Nature 2011). The laboratory is now collaborating through this new R01 project with a laboratory at the Dana Farber Cancer Research institute to define the mechanisms by which genetic associations lead to cancer initiation and progression. This highly translational research lab will seek ways to utilize the data generated in this project to impact patient care.

The desired candidate must have a terminal degree (PhD, MD, DVM, etc.) in cancer biology, cancer genetics and/or computational biology. In addition, a proficiency in state-of-the-art laboratory techniques such as ChIP-Seq and/or CRISPR-Cas genome editing is strongly desired. Ideally, the successful candidate will have both wet bench and dry bench skills as he/she will be responsible for generating and analyzing high-dimensional data sets.

The postdoctoral fellow will assume responsibility for a specific, on-going research project under the direction/guidance of his or her mentor. The postdoc experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group. Postdocs will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results.

Postdocs will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. Postdoctoral fellows also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

The Children's Hospital of Philadelphia (CHOP) Research Institute is an interdisciplinary institution dedicated to conducting basic, clinical and translational research on conditions and diseases that affect children. CHOP postdoctoral fellows receive mentored training in a rich scientific environment that includes both the CHOP and University of Pennsylvania research communities.

Interested individuals should send a cover letter, CV, and three references from past mentors/employers who can attest to their competency and skills in research to Dr. Maris at Maris@email.chop.edu.

Candidates must also complete a profile on their Web site at http://www.chop.edu/careers.

To learn more about the CHOP Research Institute and research programs visit http://www.research.chop.edu.

Funding and Career Development